Goat anti-MRP5 Antibody |
| Principle Name | MRP5 |
| Official Symbol | ABCC5 |
| All Name and Symbols | MRP5; DKFZp686C1782; ABCC5; ATP-binding cassette, sub-family C (CFTR/MRP), member 5; ABC33; EST277145; MOAT-C; MOATC; SMRP; pABC11; ATP-binding cassette, sub-family C, member 5; canalicular multispecific organic anion transporter C |
| Accession Number(s) | NP_005679.2; NP_001018881.1 |
| Peptide Sequence | KDIDIGKEYIIP, is from N Terminus |
| Human Gene ID(s) | 10057 |
| Non-Human GeneID(s) | 27416 (mouse); 116721 (rat); |
| Important Comments | This antibody is expected to recognize both reported isoforms (NP_005679.2; NP_001018881.1). |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Supplied As | lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing. |
| Applications | Pep ELISA, WB, IHC |
| Tested Species | Human |
| Peptide ELISA | antibody detection limit dilution 1 to 32000. |
| Western Blot | Approx. 150kDa band observed in Human Brain (Frontal Cortex) lysates (calculated MW of 161kDa according to NP_005679.2). Recommended concentration |
| Immunohistochemistry | In paraffin embedded Human Kidney shows membranous staining in DCT. Paraffin embedded Human Liver. Recommended concentration |
| Reference(s) | Meyer Zu Schwabedissen HE, Grube M, Heydrich B, Linnemann K, Fusch C, Kroemer HK, Jedlitschky G. Expression, localization, and function of MRP5 (ABCC5), a transporter for cyclic nucleotides, in human placenta and cultured human trophoblasts |
