Goat anti-ABCA2 Antibody |
| Principle Name | ABCA2 |
| Official Symbol | ABCA2 |
| All Name and Symbols | ABCA2; ATP-binding cassette, sub-family A (ABC1), member 2; ABC2; MGC129761; ATP-binding cassette, sub-family A, member 2; OTTHUMP00000064733 |
| Accession Number(s) | NP_001597.2; NP_997698.1 |
| Peptide Sequence | KKQSDNLEQQETEP, is from internal region |
| Human Gene ID(s) | 20 |
| Non-Human GeneID(s) | 11305 (mouse); 79248 (rat); |
| Important Comments | This antibody is expected to recognize both reported isoforms (NP_001597.2; NP_997698.1). |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Supplied As | lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing. |
| Applications | Pep ELISA, IHC |
| Tested Species | Human |
| Peptide ELISA | antibody detection limit dilution 1 to 2000. |
| Western Blot | Preliminary experiments gave an approx 35kDa band in Human Brain (Amygdala, Frontal Cortex, Hippocampus and Substantia Nigra) lysates after 0.3µg/ml antibody staining. Please note that currently we cannot find an explanation in the literatu |
| Immunohistochemistry | Paraffin embedded Human Brain (Cortex). Recommended concentration |
| Reference(s) | Macé S, Cousin E, Ricard S, Génin E, Spanakis E, Lafargue-Soubigou C, Génin B, Fournel R, Roche S, Haussy G, Massey F, Soubigou S, Bréfort G, Benoit P, Brice A, Campion D, Hollis M, Pradier L, Benavides J, Deleuze JF ABCA2 is a strong genetic risk factor for early-onset Alzheimer's disease Neurobiol Dis. 2005 Feb;18(1) |
