Goat anti-FKBP8 / FKBP38 Antibody

Item#:

dAP-1447

Size	Price	Quantity
50.0 ug	$310.00

Goat anti-FKBP8 / FKBP38 Antibody
Principle Name	FKBP8 / FKBP38
Official Symbol	FKBP8
All Name and Symbols	FKBP8; FK506 binding protein 8, 38kDa; FKBP38; FKBPr38; FK506 binding protein 8 (38kD); FK506-binding protein 8; FK506-binding protein 8 (38kD)
Accession Number(s)	NP_036313.3
Peptide Sequence	KLEPSNKTIHAELSK, is from internal region
Human Gene ID(s)	23770
Non-Human GeneID(s)	14232 (mouse); 290652 (rat);
Important Comments
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As	lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications	Pep ELISA
Tested Species
Peptide ELISA	antibody detection limit dilution 1 to 32000.
Western Blot	Preliminary experiments gave an approx 28kDa band in Human Brain (Frontal Cortex) and Rat Brain lysates after 1µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given
Reference(s)	Wang HQ, Nakaya Y, Du Z, Yamane T, Shirane M, Kudo T, Takeda M, Takebayashi K, Noda Y, Nakayama KI, Nishimura M. Interaction of presenilins with FKBP38 promotes apoptosis by reducing mitochondrial Bcl-2. Hum Mol Genet. 2005 Jul 1;14(13)