Goat anti-CHRNB1 / ACHRB Antibody

Item#:

dAP-1440

Size	Price	Quantity
50.0 ug	$310.00

Goat anti-CHRNB1 / ACHRB Antibody
Principle Name	CHRNB1 / ACHRB
Official Symbol	CHRNB1
All Name and Symbols	CHRNB1; ACHRB; cholinergic receptor, nicotinic, beta 1 (muscle) ; CHRNB; CMS1D; CMS2A; SCCMS; cholinergic receptor, nicotinic, beta polypeptide 1 (muscle); nicotinic acetylcholine receptor beta 1 subunit
Accession Number(s)	NP_000738.2
Peptide Sequence	QEQEDHDALKED, is from internal region
Human Gene ID(s)	1140
Non-Human GeneID(s)
Important Comments
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As	lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications	Pep ELISA, WB
Tested Species	Human
Peptide ELISA	antibody detection limit dilution 1 to 1000.
Western Blot	Approx 55kDa band observed in human brain (cerebellum, hippocampus, frontal cortex) lysates (calculated MW of 56.7kDa according to NP_000738.2). Recommended concentration
Reference(s)	Lou XY, Ma JZ, Payne TJ, Beuten J, Crew KM, Li MD. Gene-based analysis suggests association of the nicotinic acetylcholine receptor beta1 subunit (CHRNB1) and M1 muscarinic acetylcholine receptor (CHRM1) with vulnerability for nicotine dependence. Hum Genet. 2006 Oct;120(3)