Goat anti-Myelin Protein zero Antibody

Item#:

dAP-1405

Size	Price	Quantity
50.0 ug	$310.00

Goat anti-Myelin Protein zero Antibody
Principle Name	Myelin Protein zero
Official Symbol	MPZ
All Name and Symbols	myelin protein zero; myelin protein zero (Charcot-Marie-Tooth neuropathy 1B) ; MPZ; CHM; CMT1; CMT1B; CMT2I; CMT2J; CMT4E; CMTDI3; DSS; HMSNIB; MPP; P0
Accession Number(s)	NP_000521.1
Peptide Sequence	DHSRSTKAVSEK, is from internal region (near the C Terminus)
Human Gene ID(s)	4359
Non-Human GeneID(s)
Important Comments	The presence of this PNS protein in Rat Spinal Cord is likely due to contamination with spinal roots during extraction from the animal.
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As	lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications	Pep ELISA, WB
Tested Species	Rat
Peptide ELISA	antibody detection limit dilution 1 to 32000.
Western Blot	Approx 28kDa band observed in Rat Spinal Cord lysates (calculated MW of 28.5kDa according to Human NP_000521.1 and of 27.7kDa according to Rat NP_058723.1). Recommended concentration
Reference(s)	LeBlanc SE, Ward RM, Svaren J. Neuropathy-associated Egr2 mutants disrupt cooperative activation of myelin protein zero by Egr2 and Sox10. Mol Cell Biol. 2007 May;27(9)