Goat anti-FMR1 Antibody |
| Principle Name | FMR1 |
| Official Symbol | FMR1 |
| All Name and Symbols | FMR1; fragile X mental retardation 1 ; FMRP; FRAXA; MGC87458 |
| Accession Number(s) | NP_002015.1 |
| Peptide Sequence | RTGKDRNQKKEKPD, is from internal region (near the C Terminus) |
| Human Gene ID(s) | 2332 |
| Non-Human GeneID(s) | |
| Important Comments | |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Supplied As | lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing. |
| Applications | Pep ELISA, WB, IHC |
| Tested Species | Human |
| Peptide ELISA | antibody detection limit dilution 1 to 128000. |
| Western Blot | Approx 80kDa band observed in lysates of cell line KELLY (calculated MW of 71.2kDa according to NP_002015.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Sittler et al, Hum Mol Gene |
| Immunohistochemistry | Paraffin embedded Human Placenta. Recommended concentration |
| Reference(s) | Hanson JE, Blank M, Valenzuela RA, Garner CC, Madison DV. The functional nature of synaptic circuitry is altered in area CA3 of the hippocampus in a mouse model of Down's syndrome. J Physiol. 2007 Feb 15;579(Pt 1) |
