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Goat anti-CEP290 / NPHP6 Antibody


Item#:
dAP-1360
Size Price Quantity
50.0 ug $310.00
Goat anti-CEP290 / NPHP6 Antibody
Principle Name CEP290 / NPHP6
Official Symbol CEP290
All Name and Symbols CEP290; centrosomal protein 290kDa; 3H11Ag; FLJ13615; FLJ21979; JBTS5; JBTS6; KIAA0373; LCA10; MKS4; NPHP6; SLSN6; rd16; CTCL tumor antigen se2-2; monoclonal antibody 3H11 antigen; nephrocystin 6; nephrocystin-6; nephrocytsin-6; prostate cancer antigen T2
Accession Number(s) NP_079390.3
Peptide Sequence QSGAESTIPDADQ, is from internal region
Human Gene ID(s) 80184
Non-Human GeneID(s)
Important Comments
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA
Tested Species
Peptide ELISA antibody detection limit dilution 1 to 8000.
Western Blot Preliminary experiments in Human Kidney, Ovary and Thymus lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml). We would appreciate any feedback from people in the field - have any results been reporte
Reference(s) McEwen DP, Koenekoop RK, Khanna H, Jenkins PM, Lopez I, Swaroop A, Martens JR. Hypomorphic CEP290/NPHP6 mutations result in anosmia caused by the selective loss of G proteins in cilia of olfactory sensory neurons. Proc Natl Acad Sci U S A. 2007 Oct 2;104(40)

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