Goat anti-IGF2BP2 Antibody

Item#:

dAP-1355

Size	Price	Quantity
50.0 ug	$310.00

Goat anti-IGF2BP2 Antibody
Principle Name	IGF2BP2
Official Symbol	IGF2BP2
All Name and Symbols	IGF2BP2; insulin-like growth factor 2 mRNA binding protein 2; IMP-2; IMP2; VICKZ2; p62; IGF II mRNA binding protein 2; IGF-II mRNA-binding protein 2
Accession Number(s)	NP_006539.3; NP_001007226.1
Peptide Sequence	KQQEQKYPQGVASQR, is from C Terminus
Human Gene ID(s)	10644
Non-Human GeneID(s)	319765 (mouse);
Important Comments	This antibody is expected to recognise both reported isoforms (NP_006539.3 and NP_001007226.1).
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As	lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications	Pep ELISA, WB
Tested Species	Human
Peptide ELISA	antibody detection limit dilution 1 to 16000.
Western Blot	Approx. 60-70kDa band observed in lysates of cell line HepG2 (calculated MW of 66.1kDa according to NP_006539.3). In transfected HEK293 transiently expressing IGF2BP2 a band of approx. 65kDa is observed. This band is not observed in the non
Reference(s)	Zeggini E, et al. Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science. 2007 Jun 1;316(5829)