Goat anti-FNIP1 Antibody |
| Principle Name | FNIP1 |
| Official Symbol | FNIP1 |
| All Name and Symbols | FNIP1; folliculin interacting protein 1; DKFZp686E18167; DKFZp781P0215; KIAA1961; MGC667; folliculin-interacting protein 1 |
| Accession Number(s) | NP_001008738.2; NP_588613.2 |
| Peptide Sequence | ENISQQEREDIQN, is from internal region |
| Human Gene ID(s) | 96459 |
| Non-Human GeneID(s) | |
| Important Comments | This antibody is expected to recognise both reported isoforms (NP_001008738.2 and NP_588613.2) |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Supplied As | lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing. |
| Applications | Pep ELISA |
| Tested Species | |
| Peptide ELISA | antibody detection limit dilution 1 to 32000. |
| Western Blot | Preliminary experiments in Human Heart, Liver, Ovary and Spleen lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml). We would appreciate any feedback from people in the field - have any results been r |
| Reference(s) | Baba M, Hong SB, Sharma N, Warren MB, Nickerson ML, Iwamatsu A, Esposito D, Gillette WK, Hopkins RF 3rd, Hartley JL, Furihata M, Oishi S, Zhen W, Burke TR Jr, Linehan WM, Schmidt LS, Zbar B. Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling. Proc Natl Acad Sci U S A. 2006 Oct 17;103(42) |
