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Goat anti-KCNJ11 / KATP / Antibody
Item#:
dAP-1267
Size Price Quantity
50.0 ug $310.00
Goat anti-KCNJ11 / KATP / Antibody
Principle Name KCNJ11 / KATP /
Official Symbol KCNJ11
All Name and Symbols KCNJ11; IKATP; potassium inwardly-rectifying channel, subfamily J, member 11; BIR; HHF2; KIR6.2; MGC133230; PHHI; TNDM3; ATP-sensitive inward rectifier potassium channel 11; beta-cell inward rectifier subunit; inwardly rectifying potassium channel KIR6.2;
Accession Number(s) NP_000516.3
Peptide Sequence AEDPAKPRYRARQ, is from internal region (near the N Terminus)
Human Gene ID(s) 3767
Non-Human GeneID(s)
Important Comments This antibody is expected to recognise isoform 1 (NP_000516.3) only.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB, IHC
Tested Species Human
Peptide ELISA antibody detection limit dilution 1 to 32000.
Western Blot Approx 45-48kDa band observed in Human Skeletal Muscle lysates (calculated MW of 43.5kDa according to NP_000516.3). Recommended concentration
Immunohistochemistry In paraffin embedded Human Pancreas shows variable staining across the islet of Langerhans. Recommended concentration, 3-5µg/ml.
Reference(s) Filosa JA, Bonev AD, Straub SV, Meredith AL, Wilkerson MK, Aldrich RW, Nelson MT. Local potassium signaling couples neuronal activity to vasodilation in the brain. Nat Neurosci. 2006 Nov;9(11)

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