Goat anti-TMPRSS3 Antibody

Item#:

dAP-1247

Size	Price	Quantity
50.0 ug	$310.00

Goat anti-TMPRSS3 Antibody
Principle Name	TMPRSS3
Official Symbol	TMPRSS3
All Name and Symbols	transmembrane protease, serine 3; DFNB10; DFNB8; ECHOS1; TADG12; serine protease TADG12
Accession Number(s)	NP_076927.1; NP_115777.1; NP_115780.1; NP_115781.1
Peptide Sequence	EKIVYHSKYKPKR, is from internal region
Human Gene ID(s)	64699
Non-Human GeneID(s)	140765 (mouse);
Important Comments	This antibody is expected to recognise all four reported isoforms (NP_076927.1; NP_115777.1; NP_115780.1; NP_115781.1)
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As	lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications	Pep ELISA, WB
Tested Species	Human
Peptide ELISA	antibody detection limit dilution 1 to 32000.
Western Blot	Approx 48kDa band observed in A431 lysates (calculated MW of 49.4kDa according to NP_076927.1). Recommended concentration
Reference(s)	Lee YJ, Park D, Kim SY, Park WJ. Pathogenic mutations but not polymorphisms in congenital and childhood onset autosomal recessive deafness disrupt the proteolytic activity of TMPRSS3. J Med Genet. 2003 Aug;40(8)