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Goat anti-KCC3 / SLC12A6 Antibody
Item#:
dAP-1211
Size Price Quantity
50.0 ug $310.00
Goat anti-KCC3 / SLC12A6 Antibody
Principle Name KCC3 / SLC12A6
Official Symbol SLC12A6
All Name and Symbols SLC12A6; KCC3; solute carrier family 12 (potassium/chloride transporters), member 6 ; ACCPN; DKFZP434D2135; KCC3A; KCC3B; agenesis of corpus callosum and peripheral neuropathy (Andermann syndrome); potassium chloride cotransporter 3; potassium chloride c
Accession Number(s) NP_001035959.1; NP_001035960.1; NP_001035961.1; NP_001035962.1; NP_005126.1; NP_598408.1
Peptide Sequence SRHIDVCSKTKE, is from internal region
Human Gene ID(s) 9990
Non-Human GeneID(s)
Important Comments This antibody is expected to recognise all reported isofoms (NP_598408.1; NP_005126.1; NP_001035959.1; NP_001035961.1; NP_001035962.1); Reported variants represent identicial protein
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB, IHC
Tested Species Human
Peptide ELISA antibody detection limit dilution 1 to 16000.
Western Blot Approx 120kDa band observed in Human Heart and Kidney lysates (calculated MW ranging 121-128kDa according to NP_598408.1; NP_005126.1; NP_001035959.1; NP_001035960.1; NP_001035961.1; NP_001035962.1). Recommended concentration
Immunohistochemistry In paraffin embedded Human Heart shows staining of myocardial fibrils in transverse section. Recommended concentration, 2-4µg/ml.
Reference(s) Simard CF, Bergeron MJ, Frenette-Cotton R, Carpentier GA, Pelchat ME, Caron L, Isenring P. Homooligomeric and heterooligomeric associations between K+-Cl- cotransporter isoforms and between K+-Cl- and Na+-K+-Cl- cotransporters. J Biol Chem. 2007 Jun 22;282(25)

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