Goat anti-THRA Antibody |
| Principle Name | THRA |
| Official Symbol | THRA |
| All Name and Symbols | THRA; thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian); AR7; EAR7; ERB-T-1; ERBA; ERBA1; MGC000261; MGC43240; NR1A1; THRA1; THRA2; c-ERBA-1; ERBA-related 7; avian erythroblastic leukemia viral (v-erb-a) onc |
| Accession Number(s) | NP_955366.1; NP_003241.2 |
| Peptide Sequence | KEEMIRSLQQRP, is from internal region |
| Human Gene ID(s) | 7067 |
| Non-Human GeneID(s) | 21833 (mouse); 81812 (rat); |
| Important Comments | This antibody is expected to recognize both reported isoforms (NP_955366.1; NP_003241.2). This antibody is not expected to cross-react to THRB. |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Supplied As | lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing. |
| Applications | Pep ELISA, WB, IHC |
| Tested Species | Human |
| Peptide ELISA | antibody detection limit dilution 1 to 32000. |
| Western Blot | Approx 60+50kDa bands observed in Human Bone Marrow lysates (calculated MW of 54.8kDa according to NP_003241.2 and of 46.8kDa according to NP_955366.1). Recommended concentration |
| Immunohistochemistry | Paraffin embedded Human Tonsil and Breast. Recommended concentration |
| Reference(s) | Nishiyama K, Baba S, Yamada T, Matsushita A, Natsume H, Nakano K, Sasaki S, Nakamura H. Embryonic lethal effect of expressing a dominant negative mutant human thyroid hormone receptor alpha1 in mice. Endocr J. 2003 Oct;50(5) |
