Goat anti-KU70 / XRCC6 Antibody

Item#:

dAP-1148

Size	Price	Quantity
50.0 ug	$310.00

Goat anti-KU70 / XRCC6 Antibody
Principle Name	KU70 / XRCC6
Official Symbol	XRCC6
All Name and Symbols	XRCC6; KU70; X-ray repair complementing defective repair in Chinese hamster cells 6 (Ku autoantigen, 70kDa) ; CTC75; CTCBF; G22P1; ML8; TLAA ; ATP-dependent DNA helicase II, 70 kDa subunit; CTC box binding factor 75 kDa subunit; Ku autoantigen p70 subuni
Accession Number(s)	NP_001460.1
Peptide Sequence	YKTEGDEEAEEEQ, is from N Terminus
Human Gene ID(s)	2547
Non-Human GeneID(s)
Important Comments
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As	lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications	Pep ELISA, WB
Tested Species	Human
Peptide ELISA	antibody detection limit dilution 1 to 2000.
Western Blot	Approx 70kDa band observed in lysates of cell lines A431, HeLa and HepG2 (calculated MW of 69.8kDa according to NP_001460.1). In transfected HEK293 transiently expressing KU70 a band of approx. 70kDa is observed. This band is not observed i
Reference(s)	Ribes-Zamora A, Mihalek I, Lichtarge O, Bertuch AA. Distinct faces of the Ku heterodimer mediate DNA repair and telomeric functions. Nat Struct Mol Biol. 2007 Apr;14(4)