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Goat anti-c-Myb (aa281-294) Antibody
Item#:
dAP-1140
Size Price Quantity
50.0 ug $310.00
Goat anti-c-Myb (aa281-294) Antibody
Principle Name c-Myb (aa281-294)
Official Symbol MYB
All Name and Symbols c-myb; MYB; v-myb myeloblastosis viral oncogene homolog (avian); c-myb_CDS; efg; Avian myeloblastosis viral (v-myb) oncogene homolog; c-myb protein (140 AA); c-myb10A_CDS; c-myb13A_CDS; c-myb14A_CDS; c-myb8B_CDS; v-myb avian myeloblastosis viral oncogene
Accession Number(s) NP_001123645.1; NP_005366.2; NP_001123644.1; NP_001155128.1; NP_001155129.1; NP_001155130.1; NP_001155131.1
Peptide Sequence QRHYNDEDPEKEKR, is from internal region
Human Gene ID(s) 4602
Non-Human GeneID(s) 17863 (mouse);
Important Comments This antibody is expected to recognize isoforms 1-7 only (Numbering from NCBI RefSeq). (NP_001123645.1; NP_005366.2; NP_001123644.1; NP_001155128.1; NP_001155129.1; NP_001155130.1; NP_001155131.1)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB, IHC
Tested Species Human
Peptide ELISA antibody detection limit dilution 1 to 1000.
Western Blot Approx 70kDa band observed in Human Colon lysates (calculated MW of 72.3kDa according to NP_005366.2). Recommended concentration
Immunohistochemistry In paraffin embedded Kidney shows nuclear staining in all cells. Recommended concentration
Reference(s) Clappier E, Cuccuini W, Kalota A, Crinquette A, Cayuela JM, Dik WA, Langerak AW, Montpellier B, Nadel B, Walrafen P, Delattre O, Aurias A, Leblanc T, Dombret H, Gewirtz AM, Baruchel A, Sigaux F, Soulier J. The C-MYB locus is involved in chromosomal translocation and genomic duplications in human T-cell acute leukemia (T-ALL) - the translocation defining a new T-ALL subtype in very young children. Blood. 2007 Apr 23; [Epub ahead of print].PMID

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