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Goat anti-PTPN6 / SHP1 (internal) Antibody
Item#:
dAP-1091
Size Price Quantity
50.0 ug $310.00
Goat anti-PTPN6 / SHP1 (internal) Antibody
Principle Name PTPN6 / SHP1 (internal)
Official Symbol PTPN6
All Name and Symbols PTPN6; SHP1 ; protein tyrosine phosphatase, non-receptor type 6 ; HCP; HCPH; HPTP1C; PTP-1C; SH-PTP1; SHP-1; SHP-1L; 70 kda SHP-1L protein; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; protein-tyrosine phosphatase 1C
Accession Number(s) NP_536858.1; NP_002822.2
Peptide Sequence HTKNKREEKVKKQ, is from internal region (near the C Terminus)
Human Gene ID(s) 5777
Non-Human GeneID(s)
Important Comments This antibody is expected to recognise both reported isoforms (NP_536858.1and NP_002822.2)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB
Tested Species Human
Peptide ELISA antibody detection limit dilution 1 to 128000.
Western Blot Approx 70kDa band observed in lysates of cell lines Jurkat and U937 (calculated MW of 67.7kDa according to NP_536858.1 and 67.6kDa according to NP_002822.2). Recommended concentration
Reference(s) Dubois MJ, Bergeron S, Kim HJ, Dombrowski L, Perreault M, Fournes B, Faure R, Olivier M, Beauchemin N, Shulman GI, Siminovitch KA, Kim JK, Marette A. The SHP-1 protein tyrosine phosphatase negatively modulates glucose homeostasis. Nat Med. 2006 May;12(5)

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