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Goat anti-PTPN6 / SHP1 (internal region) Antibody
Item#:
dAP-1056
Size Price Quantity
50.0 ug $310.00
Goat anti-PTPN6 / SHP1 (internal region) Antibody
Principle Name PTPN6 / SHP1 (internal region)
Official Symbol PTPN6
All Name and Symbols PTPN6; SHP1; protein tyrosine phosphatase, non-receptor type 6 ; HCP; HCPH; HPTP1C; PTP-1C; SH-PTP1; SHP-1; SHP-1L; 70 kda SHP-1L protein; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; protein-tyrosine phosphatase 1C
Accession Number(s) NP_536858.1; NP_002822.2
Peptide Sequence KASRTSSKHKEE, is from internal region
Human Gene ID(s) 5777
Non-Human GeneID(s) 15170 (mouse); 116689 (rat);
Important Comments This antibody is expected to recognise both reported isoforms (NP_536858.1and NP_002822.2). Please note this antibody was designed using the mouse sequence, which differs by 1 amino acid from the human sequence.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB
Tested Species Human, Mouse, Rat
Peptide ELISA antibody detection limit dilution 1 to 128000.
Western Blot Approx 65kDa band observed in Human Bone Marrow and Liver lysates and in Mouse and Rat Spleen and Thymus lysates (calculated MW of 67.6kDa according to NP_536858.1and NP_002822.2). Recommended concentration
Reference(s) Dubois MJ, Bergeron S, Kim HJ, Dombrowski L, Perreault M, Fournes B, Faure R, Olivier M, Beauchemin N, Shulman GI, Siminovitch KA, Kim JK, Marette A. The SHP-1 protein tyrosine phosphatase negatively modulates glucose homeostasis. Nat Med. 2006 May;12(5)

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