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Goat anti-TMP21 / TMED10 Antibody
Item#:
dAP-1045
Size Price Quantity
50.0 ug $310.00
Goat anti-TMP21 / TMED10 Antibody
Principle Name TMP21 / TMED10
Official Symbol TMED10
All Name and Symbols TMED10; transmembrane emp24-like trafficking protein 10 (yeast); P24(DELTA); S31I125; S31III125; TMP21; Tmp-21-I ; 21 kDa transmembrane trafficking protein; transmembrane emp24 domain-containing protein 10
Accession Number(s) NP_006818.3
Peptide Sequence YLRRFFKAKKLIE, is from C Terminus
Human Gene ID(s) 10972
Non-Human GeneID(s) 68581 (mouse); 84599 (rat);
Important Comments
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA
Tested Species
Peptide ELISA antibody detection limit dilution 1 to 1000.
Western Blot Preliminary experiments gave an approx 75kDa band in Human and Rat Pancreas lysates after 1µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size
Reference(s) Chen F, Hasegawa H, Schmitt-Ulms G, Kawarai T, Bohm C, Katayama T, Gu Y, Sanjo N, Glista M, Rogaeva E, Wakutani Y, Pardossi-Piquard R, Ruan X, Tandon A, Checler F, Marambaud P, Hansen K, Westaway D, St George-Hyslop P, Fraser P. TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity. Nature. 2006 Apr 27;440(7088)

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