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Goat anti-STS2 / TULA (internal) Antibody


Item#:
dAP-1041
Size Price Quantity
50.0 ug $310.00
Goat anti-STS2 / TULA (internal) Antibody
Principle Name STS2 / TULA (internal)
Official Symbol UBASH3A
All Name and Symbols TULA ; STS2 CBL-interacting protein 4; UBASH3A; ubiquitin associated and SH3 domain containing, A ; T-cell ubiquitin ligand protein; Suppressor of T-cell receptor signaling 2; CLIP4
Accession Number(s) NP_061834.1; NP_001001895.1
Peptide Sequence QQCSTPDGKYYRPD, is from internal region
Human Gene ID(s) 53347
Non-Human GeneID(s)
Important Comments This antibody is expected to recognize both reported isoforms (NP_061834.1 and NP_001001895.1).
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, IHC
Tested Species Human
Peptide ELISA antibody detection limit dilution 1 to 64000.
Western Blot Preliminary experiments gave an approx 48kDa band in lysates of B-cell line Daudi after 0.1µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size
Immunohistochemistry In paraffin embedded Human Spleen shows cytoplasm staining of T-cells eccentrically gathered around an artery. Recommended concentration
Reference(s) Kowanetz K, Crosetto N, Haglund K, Schmidt MH, Heldin CH, Dikic I. Suppressors of T-cell receptor signaling Sts-1 and Sts-2 bind to Cbl and inhibit endocytosis of receptor tyrosine kinases. J Biol Chem. 2004 Jul 30;279(31)

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