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Goat anti-SMN1 / SMN2 Antibody
Item#:
dAP-1036
Size Price Quantity
50.0 ug $310.00
Goat anti-SMN1 / SMN2 Antibody
Principle Name SMN1 / SMN2
Official Symbol SMN1 / SMN2
All Name and Symbols SMN1; survival of motor neuron 1, telomeric; BCD541; SMA1; SMA2; SMA3; SMA4; SMN; SMNT; T-BCD541; gemin 1; SMN2; survival of motor neuron 2, centromeric; BCD541; C-BCD541; SMNC;
Accession Number(s) NP_075012.1; NP_000335.1; NP_075013.1; NP_075014.1; NP_075015.1; NP_059107.1
Peptide Sequence DESENSRSPGNKSDN, is from internal region
Human Gene ID(s) 6606; 6607
Non-Human GeneID(s)
Important Comments This antibody is expected to recognise isoforms b and d of SMN1 (NP_075012.1 and NP_000335.1) and all reported isoforms of SMN2 (NP_075013.1, NP_075014.1, NP_075015.1 and NP_059107.1).
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB
Tested Species Human
Peptide ELISA antibody detection limit dilution 1 to 32000.
Western Blot Approx 26kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 28.5kDa according to NP_075012.1 and NP_075014.1). Recommended concentration
Reference(s) Setola V, Terao M, Locatelli D, Bassanini S, Garattini E, Battaglia G. Axonal-SMN (a-SMN), a protein isoform of the survival motor neuron gene, is specifically involved in axonogenesis. Proc Natl Acad Sci U S A. 2007 Feb 6;104(6)

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