Goat anti-HAP1 Antibody |
| Principle Name | HAP1 |
| Official Symbol | HAP1 |
| All Name and Symbols | HAP1; huntingtin-associated protein 1 (neuroan 1); HAP2; HIP5; HLP; hHLP1; huntingtin-associated protein 1; huntingtin-associated protein 2; neuroan 1 |
| Accession Number(s) | NP_003940.2; NP_817084.1 |
| Peptide Sequence | RYDFRYSEDREQ, is from internal region |
| Human Gene ID(s) | 9001 |
| Non-Human GeneID(s) | |
| Important Comments | This antibody is expected to recognize all reported isoforms (NP_003940.1, NP_817084.1) |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Supplied As | lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing. |
| Applications | Pep ELISA, WB, IHC |
| Tested Species | Human |
| Peptide ELISA | antibody detection limit dilution 1 to 32000. |
| Western Blot | Approx 70kDa band observed in Human Brain (Frontal Cortex and Hippocampus) lysates (calculated MW of 69.6kDa according to NP_817084.1). Recommended concentration |
| Immunohistochemistry | Paraffin embedded Human Brain (Cortex). Recommended concentration |
| Reference(s) | Takeshita Y, Fujinaga R, Zhao C, Yanai A, Shinoda K. Huntingtin-associated protein 1 (HAP1) interacts with androgen receptor (AR) and suppresses SBMA-mutant-AR-induced apoptosis. Hum Mol Genet. 2006 Aug 1;15(15) |