Goat anti-PAK1 Antibody |
| Principle Name | PAK1 |
| Official Symbol | PAK1 |
| All Name and Symbols | PAK1; p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) ; MGC130000; MGC130001; PAKalpha ; p21-activated kinase 1; p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related) |
| Accession Number(s) | NP_002567.3 |
| Peptide Sequence | NTEKQKKKPKMSDE, is from internal region |
| Human Gene ID(s) | 5058 |
| Non-Human GeneID(s) | 18479 (mouse); 29431 (rat); |
| Important Comments | No cross-reactivity exptected with PAK3 |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Supplied As | lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing. |
| Applications | Pep ELISA, WB |
| Tested Species | Human, Mouse, Rat |
| Peptide ELISA | antibody detection limit dilution 1 to 1000. |
| Western Blot | Approx 65kDa band observed in Human Brain (Cerebral Cortex and Hippocampus) lysates (calculated MW of 60.6kDa according to NP_002567.3). Recommended concentration |
| Reference(s) | Zhao L, Ma QL, Calon F, Harris-White ME, Yang F, Lim GP, Morihara T, Ubeda OJ, Ambegaokar S, Hansen JE, Weisbart RH, Teter B, Frautschy SA, Cole GM. Role of p21-activated kinase pathway defects in the cognitive deficits of Alzheimer disease. Nat Neurosci. 2006 Feb;9(2) |
