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Goat anti-TAK1 / MAP3K7 Antibody
Item#:
dAP-0859
Size Price Quantity
50.0 ug $310.00
Goat anti-TAK1 / MAP3K7 Antibody
Principle Name TAK1 / MAP3K7
Official Symbol MAP3K7
All Name and Symbols MAP3K7 ; TAK1; mitogen-activated protein kinase kinase kinase 7 ; TGF1a ; TGF-beta activated kinase 1; transforming growth factor-beta-activated kinase 1
Accession Number(s) NP_003179.1; NP_663304.1
Peptide Sequence AELDQDEKDQQNT, is from internal region
Human Gene ID(s) 6885
Non-Human GeneID(s) 26409 (mouse);
Important Comments This antibody is expected to recognise isoform A (NP_003179.1) and isoform B (NP_663304.1).
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB Trf
Tested Species Human
Peptide ELISA antibody detection limit dilution 1 to 8000.
Western Blot In transfected HEK293 transiently expressing full-length Human MAP3K7 (myc and DYKDDDDK tagged), a band of approx. 75kDa was observed. No bands were observed in mock-transfected HEK293 and the same band was observed using anti-DYKDDDDK tag
Reference(s) Omori E, Matsumoto K, Sanjo H, Sato S, Akira S, Smart RC, Ninomiya-Tsuji J. TAK1 is a master regulator of epidermal homeostasis involving skin inflammation and apoptosis. J Biol Chem. 2006 May 4; [Epub ahead of print] .PMID

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