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Goat anti-HRS / HGS Antibody


Item#:
dAP-0837
Size Price Quantity
50.0 ug $310.00
Goat anti-HRS / HGS Antibody
Principle Name HRS / HGS
Official Symbol HGS
All Name and Symbols HGS; hepatocyte growth factor-regulated tyrosine kinase substrate ; HGNC
Accession Number(s) NP_004703.1
Peptide Sequence NRNYWEKKQEEARK, is from internal region
Human Gene ID(s) 9146
Non-Human GeneID(s) 15239 (mouse); 56084 (rat);
Important Comments
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, IHC
Tested Species Human
Peptide ELISA antibody detection limit dilution 1 to 32000.
Western Blot Preliminary experiments gave bands at approx 140kDa and 26kDa in Human lysates of monocytic leukemia cell line U937 after 0.3µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the bands w
Immunohistochemistry In paraffin embedded Human Testis shows strong staining of Leydig cells. Recommended concentration
Reference(s) Kobayashi H, Tanaka N, Asao H, Miura S, Kyuuma M, Semura K, Ishii N, Sugamura K. Hrs, a mammalian master molecule in vesicular transport and protein sorting, suppresses the degradation of ESCRT proteins signal transducing adaptor molecule 1 and 2. J Biol Chem. 2005 Mar 18;280(11)

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