Goat anti-Tryptophan hydroxylase 2 / TPH2 Antibody

Item#:

dAP-0750

Size	Price	Quantity
50.0 ug	$310.00

Goat anti-Tryptophan hydroxylase 2 / TPH2 Antibody
Principle Name	Tryptophan hydroxylase 2 / TPH2
Official Symbol	TPH2
All Name and Symbols	TPH2; tryptophan hydroxylase 2; HGNC
Accession Number(s)	NP_775489.2
Peptide Sequence	NKPNSGKNDDKGNK, is from internal region
Human Gene ID(s)	121278
Non-Human GeneID(s)
Important Comments
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As	lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications	Pep ELISA, IHC
Tested Species	Human
Peptide ELISA	antibody detection limit dilution 1 to 16000.
Western Blot	Preliminary experiments in human brain lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml).
Immunohistochemistry	In paraffin embedded Human Brain Stem shows layered neuronal staining. Recommended concentration
Reference(s)	Zhou Z, Roy A, Lipsky R, Kuchipudi K, Zhu G, Taubman J, Enoch MA, Virkkunen M, Goldman D. Haplotype-based linkage of tryptophan hydroxylase 2 to suicide attempt, major depression, and cerebrospinal fluid 5-hydroxyindoleacetic acid in 4 populations. Arch Gen Psychiatry. 2005 Oct;62(10)