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Goat anti-Cannabinoid Receptor 1 Antibody
Item#:
dAP-0746
Size Price Quantity
50.0 ug $310.00
Goat anti-Cannabinoid Receptor 1 Antibody
Principle Name Cannabinoid Receptor 1
Official Symbol CNR1
All Name and Symbols cannabinoid receptor 1 (brain); CNR1; HGNC
Accession Number(s) NP_057167.2; NP_001153732.1; NP_001153731.1; NP_001153730.1; NP_001153698.1; NP_149421.1
Peptide Sequence HTSEDGKVQVTRPDQ, is from internal region
Human Gene ID(s) 1268
Non-Human GeneID(s) 12801 (mouse); 25248 (rat);
Important Comments This antibody is expected to recognise both reported isoforms. Isoform a (NP_057167.2; NP_001153732.1; NP_001153731.1; NP_001153730.1; NP_001153698.1) and isoform b (NP_149421.1).
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB
Tested Species Rat
Peptide ELISA antibody detection limit dilution 1 to 32000.
Western Blot Approx 65kDa band observed in Rat Brain lysates (calculated MW of 52.7kDa according to Rat NP_036916.1 and 52.9kDa according to Human NP_057167.2). The observed molecular weight corresponds to earlier findings in literature with different a
Reference(s) Ledent C, Valverde O, Cossu G, Petitet F, Aubert JF, Beslot F, Bohme GA, Imperato A, Pedrazzini T, Roques BP, Vassart G, Fratta W, Parmentier M Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice. Science. 1999 Jan 15;283(5400)

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