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Goat anti-CBX1 / HP1-Beta Antibody
Item#:
dAP-0729
Size Price Quantity
50.0 ug $310.00
Goat anti-CBX1 / HP1-Beta Antibody
Principle Name CBX1 / HP1-Beta
Official Symbol CBX1
All Name and Symbols CBX1; HP1-BETA; chromobox homolog 1 (HP1 beta homolog Drosophila ); HGNC
Accession Number(s) NP_006798.1; NP_001120700.1
Peptide Sequence QSQKTAHETDKSE, is from internal region
Human Gene ID(s) 10951
Non-Human GeneID(s) 12412 (mouse); 360609 (rat);
Important Comments Variants (NP_006798.1; NP_001120700.1) encode the same protein.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB, IHC
Tested Species Human
Peptide ELISA antibody detection limit dilution 1 to 32000.
Western Blot Approx. 25kDa band observed in lysates of A431, HeLa and HepG2 (calculated MW of 25kDa according to NP_006798.1). Recommended concentration
Immunohistochemistry In paraffin embedded Human Placenta shows strong nuclear staining in trophoblasts. Recommended concentration, 2-3µg/ml.
Reference(s) Sharma GG, Hwang KK, Pandita RK, Gupta A, Dhar S, Parenteau J, Agarwal M, Worman HJ, Wellinger RJ, Pandita TK. Human heterochromatin protein 1 isoforms HP1(Hsalpha) and HP1(Hsbeta) interfere with hTERT-telomere interactions and correlate with changes in cell growth and response to ionizing radiation. Mol Cell Biol. 2003 Nov;23(22)

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