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Goat anti-Arrestin beta 2 Antibody


Item#:
dAP-0640
Size Price Quantity
50.0 ug $310.00
Goat anti-Arrestin beta 2 Antibody
Principle Name Arrestin beta 2
Official Symbol ARRB2
All Name and Symbols ARRB2; arrestin, beta 2; HGNC
Accession Number(s) NP_004304.1; NP_945355.1; NP_001244257.1; NP_001244259.1; NP_001244260.1
Peptide Sequence HDHIPLPRPQS, is from internal region
Human Gene ID(s) 409
Non-Human GeneID(s) 216869 (mouse); 25388 (rat);
Important Comments This antibody is expected to recognise both reported isoforms 1, 2, 3, 5 and 6 (NP_004304.1; NP_945355.1; NP_001244257.1; NP_001244259.1; NP_001244260.1). No crossreactivity is expected with Arrestin beta 1.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB, IHC
Tested Species Human, Mouse, Rat
Peptide ELISA antibody detection limit dilution 1 to 32000.
Western Blot Approx 40kDa band observed in Human Brain lysates (calculated MW of 46.1kDa according to NP_004304.1 and 44.4 according to NP_945355.1). Recommended concentration
Immunohistochemistry In paraffin embedded Human Cerebellum shows mainly nuclear staining of purkinje cells and neuronal cells in the Molecular Layer. Recommended concentration
Reference(s) Lefkowitz RJ, Shenoy SK. Transduction of receptor signals by beta-arrestins. Science. 2005 Apr 22;308(5721)

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