Goat anti-Survivin / BIRC5 Antibody

Item#:

dAP-0581

Size	Price	Quantity
50.0 ug	$310.00

Goat anti-Survivin / BIRC5 Antibody
Principle Name	Survivin / BIRC5
Official Symbol	BIRC5
All Name and Symbols	BIRC5; survivin; API4; EPR-1; baculoviral IAP repeat-containing 5 (survivin); apoptosis inhibitor 4; baculoviral IAP repeat-containing 5; baculoviral IAP repeat-containing protein 5; survivin variant 3 alpha
Accession Number(s)	NP_001159.2; NP_001012271.1
Peptide Sequence	CVRRAIEQLAAMD, is from C Terminus
Human Gene ID(s)	332
Non-Human GeneID(s)
Important Comments	This antibody is expected to recognize the reported isoforms 1 (NP_001159.2) and isoform 3 (NP_001012271.1).
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As	lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications	Pep ELISA, WB
Tested Species	Human
Peptide ELISA	antibody detection limit dilution 1 to 16000.
Western Blot	Approx 18kDa band observed in Human T cell line MOLT4 lysates (calculated MW of 16.4kDa according to NP_001159.2 and 18.6kDa according to NP_001012271.1). Recommended concentration
Reference(s)	Li F, Ambrosini G, Chu EY, Plescia J, Tognin S, Marchisio PC, Altieri DC. Control of apoptosis and mitotic spindle checkpoint by survivin. Nature. 1998 Dec 10;396(6711)