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Goat anti-LXR beta / NR1H2 Antibody
Item#:
dAP-0557
Size Price Quantity
50.0 ug $310.00
Goat anti-LXR beta / NR1H2 Antibody
Principle Name LXR beta / NR1H2
Official Symbol NR1H2
All Name and Symbols NR1H2; LXR-b; NER; UNR; NER-I; RIP15; nuclear receptor subfamily 1, group H, member 2; ubiquitously-expressed nuclear receptor; LXRB; LX receptor beta; liver X receptor beta; liver X receptor-beta; nuclear orphan receptor LXR-beta; oxysterols receptor LXR
Accession Number(s) NP_009052.3
Peptide Sequence SSPTTSSLDTPLPGC, is from N Terminus
Human Gene ID(s) 7376
Non-Human GeneID(s)
Important Comments Based on the peptide used, this antibody is expected to be specific for LXR beta and not to cross-react with LXR alpha.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB, IHC
Tested Species Human
Peptide ELISA antibody detection limit dilution 1 to 64000.
Western Blot Experiments gave a band at approx 80kDa and a weak band at approx 60kDa in Human Bone Marrow lysate after 1µg/ml antibody staining. These bands correspond to earlier findings with different antibodies (PMID
Immunohistochemistry In paraffin embedded Human Spleen shows nucleolar staining. Recommended concentration
Reference(s) Tangirala RK, Bischoff ED, Joseph SB, Wagner BL, Walczak R, Laffitte BA, Daige CL, Thomas D, Heyman RA, Mangelsdorf DJ, Wang X, Lusis AJ, Tontonoz P, Schulman IG. Identification of macrophage liver X receptors as inhibitors of atherosclerosis. Proc Natl Acad Sci U S A. 2002 Sep 3;99(18)

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