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Goat anti-LXR alpha / LXR beta Antibody
Item#:
dAP-0547
Size Price Quantity
50.0 ug $310.00
Goat anti-LXR alpha / LXR beta Antibody
Principle Name LXR alpha / LXR beta
Official Symbol NR1H3; NR1H2
All Name and Symbols NR1H3; LXRA; LXR-a; RLD-1; nuclear receptor subfamily 1, group H, member 3; liver X receptor, alpha; NR1H2; NER; UNR; LXR-b; NER-I; RIP15; nuclear receptor subfamily 1, group H, member 2; ubiquitously-expressed nuclear receptor / NR1H2; NER; UNR; LXR-b; N
Accession Number(s) NP_005684.2; NP_009052.3
Peptide Sequence CRLQDKKLPPLLSEI, is from internal region
Human Gene ID(s) 10062; 7376
Non-Human GeneID(s)
Important Comments This antibody is expected to recognise an epitope corresponding to aa 429-442 of human LXR alpha protein (NP_005684.2) and to aa 443-456 of human LXR beta protein (NP_009052.3).
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB
Tested Species Human
Peptide ELISA antibody detection limit dilution 1 to 32000.
Western Blot Approx 55kDa band observed in Human Spleen lysates (calculated MW of 50.5kDa according to NP_005684.2 and 50.1kDa according to NP_009052.3). Recommended concentration
Reference(s) Tangirala RK, Bischoff ED, Joseph SB, Wagner BL, Walczak R, Laffitte BA, Daige CL, Thomas D, Heyman RA, Mangelsdorf DJ, Wang X, Lusis AJ, Tontonoz P, Schulman IG. Identification of macrophage liver X receptors as inhibitors of atherosclerosis. Proc Natl Acad Sci U S A. 2002 Sep 3;99(18)

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