Goat anti-LAT1 Antibody |
| Principle Name | LAT1 |
| Official Symbol | LAT |
| All Name and Symbols | LAT1; LAT; linker for activation of T cells; pp36; 36 kDa phospho-tyrosine adaptor protein; linker for activation of T-cells family member 1 |
| Accession Number(s) | NP_055202.1; NP_001014987.1; NP_001014989.1; NP_001014988.1 |
| Peptide Sequence | GAPDYENLQELN, is from C Terminus |
| Human Gene ID(s) | 27040 |
| Non-Human GeneID(s) | |
| Important Comments | This antibody is expected to recognize isoform a (NP_055202.1), isoform b (NP_001014987.1 and NP_001014989.1) and isoform c (NP_001014988.1). |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Supplied As | lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing. |
| Applications | Pep ELISA, WB |
| Tested Species | Human |
| Peptide ELISA | antibody detection limit dilution 1 to 2000. |
| Western Blot | Approx 37kDa band observed in Human Peripheral Brood Mononucleocytes lysates (calculated MW of 27.9kDa according to NP_055202.1). The observed molecular weight corresponds to earlier findings with different antibodies from other commercial |
| Reference(s) | Finco TS, Kadlecek T, Zhang W, Samelson LE, Weiss A. LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway. Immunity. 1998 Nov;9(5) |
