Goat anti-MCL1 Antibody |
| Principle Name | MCL1 |
| Official Symbol | MCL1 |
| All Name and Symbols | MCL1; TM; EAT; MCL1L; MCL1S; MGC1839; MGC104264; myeloid cell leukemia sequence 1 (BCL2-related); induced myeloid leukemia cell differentiation protein Mcl-1; myeloid cell leukemia sequence 1; myeloid cell leukemia sequence 1, isoform 1; BCL2L3; Mcl-1 |
| Accession Number(s) | NP_068779.1; NP_001184249.1 |
| Peptide Sequence | AGVGAGLAYLIR, is from C Terminus |
| Human Gene ID(s) | 4170 |
| Non-Human GeneID(s) | 17210 (mouse); |
| Important Comments | This antibody is expected to recognise reported isoform 1 (NP_068779.1) and isoform 3 (NP_001184249.1). |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Supplied As | lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing. |
| Applications | Pep ELISA, WB |
| Tested Species | Human |
| Peptide ELISA | antibody detection limit dilution 1 to 2000. |
| Western Blot | Approx 35kDa band observed in lysates of Human Lung (calculated MW of 37.3kDa according to NP_068779.1). Recommended concentration |
| Reference(s) | Opferman JT, Letai A, Beard C, Sorcinelli MD, Ong CC, Korsmeyer SJ. Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1. Nature. 2003 Dec 11;426(6967) |
