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Goat anti-KMT2D/MLL2 Antibody


Item#:
dAP-0437
Size Price Quantity
50.0 ug $310.00
Goat anti-KMT2D/MLL2 Antibody
Principle Name KMT2D/MLL2
Official Symbol KMT2D
All Name and Symbols MLL2; myeloid/lymphoid or mixed-lineage leukemia 2; ALR; ALL1-related gene; AAD10; CAGL114; KMT2D; MLL4; TNRC21; ALL1-related; trinucleotide repeat containing 21, KMS, KABUK1, Lysine methyltransferase 2D
Accession Number(s) NP_003473.3
Peptide Sequence DSQNLAGEDKDSQ, is from N Terminus
Human Gene ID(s) 8085
Non-Human GeneID(s)
Important Comments The immunizing peptide was designed from NP_003473.1. Since then the sequence has changed in the databases and currently differs at two locations in NP_003473.3.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, IHC
Tested Species Human
Peptide ELISA antibody detection limit dilution 1 to 16000.
Western Blot Using our routine western blotting protocol we would not expect to reliably detect proteins larger than 250kDa (calculated MW of approx. 593KDa according to NP_003473.3).
Immunohistochemistry In paraffin embedded Human Placenta shows nuclear stainng in the trophoblasts . Similar nuclear patches are observed in Human Liver. Recommended concentration
Reference(s) Prasad R, Zhadanov AB, Sedkov Y, Bullrich F, Druck T, Rallapalli R, Yano T, Alder H, Croce CM, Huebner K, Mazo A, Canaani E. Structure and expression pattern of human ALR, a novel gene with strong homology to ALL-1 involved in acute leukemia and to Drosophila trithorax. Oncogene. 1997 Jul 31;15(5)

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