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Goat anti-SH2-B / SH2B1 (isoform2) Antibody
Item#:
dAP-0331
Size Price Quantity
50.0 ug $310.00
Goat anti-SH2-B / SH2B1 (isoform2) Antibody
Principle Name SH2-B / SH2B1 (isoform2)
Official Symbol SH2B1
All Name and Symbols SH2B1; SH2B; SH2-B; DKFZP547G1110; SH2-B homolog; SH2-B alpha signaling protein; SH2-B gamma signaling protein; likely ortholog of mouse SH2 domain-containing putative adapter SH2-B; SH2B adaptor protein 1; DKFZp547G1110; FLJ30542; KIAA1299; PSM; SH2 doma
Accession Number(s) NP_056318.2
Peptide Sequence PFGASDCVTDHLP, is from C Terminus
Human Gene ID(s) 25970
Non-Human GeneID(s) 20399 (mouse);
Important Comments This antibody is expected to recognise isoform 2 (NP_056318.2) only. Reported variants represent identical protein (NP_001139268.1; NP_056318.2; NP_001139284.1).
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA
Tested Species
Peptide ELISA antibody detection limit dilution 1 to 32000.
Western Blot Preliminary experiments gave an approx 45-48kDa band in human heart lysate at 1ug/ml. Please note that currently we cannot find an explanation in the literature for the band we observe given the predicted size of 70.6kDa according to NP_056
Reference(s) O'Brien KB, O'Shea JJ, Carter-Su C. SH2-B family members differentially regulate JAK family tyrosine kinases. J Biol Chem 2002 Mar 8;277(10)

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