Goat anti-IRF6 Antibody |
| Principle Name | IRF6 |
| Official Symbol | IRF6 |
| All Name and Symbols | IRF6; interferon regulatory factor 6; LPS; PIT; PPS; VWS; OFC6 |
| Accession Number(s) | NP_006138.1 |
| Peptide Sequence | TPSMQLPPALPPQ, is from C Terminus |
| Human Gene ID(s) | 3664 |
| Non-Human GeneID(s) | 54139 (mouse); |
| Important Comments | |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Supplied As | lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing. |
| Applications | Pep ELISA, WB, IHC |
| Tested Species | Human |
| Peptide ELISA | antibody detection limit dilution 1 to 32000. |
| Western Blot | Approx 60kDa band observed in Human Ovary lysates (calculated MW of 53.1kDa according to NP_006138.1). In transfected HEK293 transiently expressing IRF6 a band of approx. 55kDa is observed. This band is not observed in the non-transfected H |
| Immunohistochemistry | In paraffin embedded Human Kidney shows strong nuclear staining in DCT and glomerulus. Recommended concentration |
| Reference(s) | Kondo S, Schutte BC, Richardson RJ, Bjork BC, Knight AS, Watanabe Y, Howard E, de Lima RL, Daack-Hirsch S, Sander A, McDonald-McGinn DM, Zackai EH, Lammer EJ, Aylsworth AS, Ardinger HH, Lidral AC, Pober BR, Moreno L, Arcos-Burgos M, Valencia C, Houdayer C Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes. Nat Genet. 2002 Oct;32(2) |
