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Goat anti-GIPC1 / NIP Antibody


Item#:
dAP-0273
Size Price Quantity
50.0 ug $310.00
Goat anti-GIPC1 / NIP Antibody
Principle Name GIPC1 / NIP
Official Symbol GIPC1
All Name and Symbols GIPC1; NIP; GIPC PDZ domain containing family, member 1; C19orf3; GIPC; GLUT1CBP; Hs.6454; IIP-1; MGC15889; MGC3774; RGS19IP1; SEMCAP; SYNECTIIN; TIP-2; GLUT1 C-terminal binding protein; IGF-1 receptor interacting protein 1; regulator of G-protein signall
Accession Number(s) NP_005707.1; NP_974197.1; NP_974199.1; NP_974196.1; NP_974198.1; NP_974223.1
Peptide Sequence GAIGDAKVGRY, is from C Terminus
Human Gene ID(s) 10755
Non-Human GeneID(s) 67903 (mouse); 83823 (rat);
Important Comments This antibody is expected to recognize both isoform 1 (NP_005707.1, NP_974197.1 and NP_974199.1) and isoform 2 (NP_974196.1, NP_974198.1 and NP_974223.1).
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB
Tested Species Human
Peptide ELISA antibody detection limit dilution 1 to 128000.
Western Blot Approx 38kDa and strong 23-24kDa bands observed in lysates of cell line HeLa, and approx 24kDa also observed in Human Pancreas, Kidney and Muscle lysates (calculated MW of 36.0kDa according to NP_005707.1, NP_974197.1 and NP_974199.1 and 26
Reference(s) De Vries L, Lou X, Zhao G, Zheng B, Farquhar MG. GIPC, a PDZ domain containing protein, interacts specifically with the C terminus of RGS-GAIP. Proc Natl Acad Sci U S A. 1998 Oct 13;95(21)

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