Goat anti-PMS1 Antibody |
| Principle Name | PMS1 |
| Official Symbol | PMS1 |
| All Name and Symbols | PMS1; PMS1 postmeiotic segregation increased 1 (S. cerevisiae); PMSL1; hPMS1; HNPCC3; postmeiotic segregation 1; human homolog of yeast mutL; MLH1; DKFZp781M0253; FLJ98259; mismatch repair gene PMSL1; postmeiotic segregation 1; rhabdomyosarcoma antigen MU |
| Accession Number(s) | NP_000525.1; NP_001121615.1; NP_001121616.1 |
| Peptide Sequence | RPFFHHLTYLPETT, is from C Terminus |
| Human Gene ID(s) | 5378 |
| Non-Human GeneID(s) | |
| Important Comments | This antibody is expected to recognise all reported isoforms. |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Supplied As | lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing. |
| Applications | Pep ELISA |
| Tested Species | |
| Peptide ELISA | antibody detection limit dilution 1 to 32000. |
| Western Blot | No signal obtained yet but low background observed in Human Brain and Kidney extracts at up to 2µg/ml. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? |
| Reference(s) | Nicolaides NC, Papadopoulos N, Liu B, Wei YF, Carter KC, Ruben SM, Rosen CA, Haseltine WA, Fleischmann RD, Fraser CMl. Mutations of two PMS homologues in hereditary nonpolyposis colon cancer. Nature. 1994 Sep 1;371(6492) |