| Product Name | Signal-Regulatory Protein Alpha Human Recombinant |
| Synonyms | Signal-Regulatory Protein Alpha, SHPS1, CD172
Antigen-Like Family Member A, Inhibitory Receptor SHPS-1, Macrophage Fusion
Receptor, PTPNS1, SIRP, P84, BIT, MFR,
Brain-Immunoglobulin-Like Molecule With Tyrosine-Based
Activation Motifs, Brain Ig-Like Molecule With Tyrosine-Based Activation
Motifs, Protein Tyrosine Phosphatase, Non-Receptor Type Substrate 1, Tyrosine-Protein
Phosphatase Non-Receptor Type Substrate 1, Tyrosine Phosphatase SHP Substrate
1, Signal-Regulatory Protein Alpha-1 , ignal-Regulatory Protein Alpha-2, Signal-Regulatory
Protein Alpha-3, SHP Substrate 1, CD172a Antigen, Myd-1 Antigen, MyD-1 Antigen,
Sirp-Alpha-1, Sirp-Alpha-2, Sirp-Alpha-3, CD172A, SHPS-1, MYD-1, MYD1, Tyrosine-protein
phosphatase non-receptor type substrate 1. |
| Description | SIRPA Human Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 370 amino acids (27-373 a.a) and
having a molecular mass of 40.4kDa.
SIRPA is fused to a 23 amino acid His-tag at N-terminus
& purified by proprietary chromatographic techniques. |
| Uniprot Accesion Number | P78324 |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSGVAGEEE LQVIQPDKSV LVAAGETATL RCTATSLIPV GPIQWFRGAG
PGRELIYNQK EGHFPRVTTV SDLTKRNNMD FSIRIGNITP ADAGTYYCVK FRKGSPDDVE FKSGAGTELS
VRAKPSAPVV SGPAARATPQ HTVSFTCESH GFSPRDITLK
WFKNGNELSD FQTNVDPVGE SVSYSIHSTA KVVLTREDVH SQVICEVAHV
TLQGDPLRGT ANLSETIRVP PTLEVTQQPV RAENQVNVTC QVRKFYPQRL QLTWLENGNV SRTETASTVT
ENKDGTYNWM SWLLVNVSAH RDDVKLTCQV EHDGQPAVSK SHDLKVSAHP KEQGSNTAAE
NTGSNERNIY. |
| Source | Escherichia Coli. |
| Physical Appearance and Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Formulation and Purity | SIRPA protein solution (0.5mg/ml) containing PBS buffer
(pH 7.4), 10% glycerol and 1mM DTT. Greater than 90.0% as determined by SDS-PAGE. |
| Application | |
| Solubility | |
| Biological Activity | |
| Shipping Format and Condition | Lyophilized powder at room temperature. |
| Usage Statement | Our products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
