Product Name | Furin Human Recombinant |
Synonyms | Furin
(Paired Basic Amino Acid Cleaving Enzyme), PCSK3, PACE, FUR, Paired Basic Amino
Acid Residue-Cleaving Enzyme, EC 3.4.21.75, Paired Basic Amino Acid Cleaving
Enzyme (Furin, Membrane Associated Receptor Protein), Proprotein Convertase
Subtilisin/Kexin Type 3, Furin, Membrane Associated Receptor Protein, Dibasic
Processing Enzyme, Dibasic-Processing Enzyme, FES Upstream Region, EC 3.4.21, Furin,
SPC1, Dibasic-processing enzyme, Paired basic amino acid residue-cleaving
enzyme. |
Description | FURIN Human Recombinant produced in E.Coli is a single, non-glycosylated
polypeptide chain containing 645 amino acids (108-715 a.a) and having a
molecular mass of 69.8kDa.
FURIN is fused to a 37
amino acid His-tag at N-terminus & purified by proprietary chromatographic
techniques. |
Uniprot Accesion Number | P09958 |
Amino Acid Sequence | MRGSHHHHHH
GMASMTGGQQ MGRDLYDDDD KDRWGSMDVY QEPTDPKFPQ QWYLSGVTQR DLNVKAAWAQ GYTGHGIVVS
ILDDGIEKNH PDLAGNYDPG ASFDVNDQDP DPQPRYTQMN DNRHGTRCAG EVAAVANNGV CGVGVAYNAR
IGGVRMLDGE VTDAVEARSL GLNPNHIHIY SASWGPEDDG KTVDGPARLA EEAFFRGVSQ GRGGLGSIFV
WASGNGGREH DSCNCDGYTN SIYTLSISSA TQFGNVPWYS EACSSTLATT YSSGNQNEKQ IVTTDLRQKC
TESHTGTSAS APLAAGIIAL TLEANKNLTW RDMQHLVVQT SKPAHLNAND WATNGVGRKV SHSYGYGLLD
AGAMVALAQN WTTVAPQRKC IIDILTEPKD IGKRLEVRKT VTACLGEPNH ITRLEHAQAR LTLSYNRRGD
LAIHLVSPMG TRSTLLAARP HDYSADGFND WAFMTTHSWD EDPSGEWVLE IENTSEANNY GTLTKFTLVL
YGTAPEGLPV PPESSGCKTL TSSQACVVCE EGFSLHQKSC VQHCPPGFAP QVLDTHYSTE NDVETIRASV
CAPCHASCAT CQGPALTDCL SCPSHASLDP VEQTCSRQSQ SSRESPPQQQ PPRLPPEVEA GQRLRAGLLP
SHLPE. |
Source | Escherichia Coli. |
Physical Appearance and Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
Formulation and Purity | FURIN
protein solution (1mg/ml) containing 20mM Tris-HCl (pH8.0) and 10% glycerol. Greater than 85.0% as determined by SDS-PAGE. |
Application | |
Solubility | |
Biological Activity | |
Shipping Format and Condition | Lyophilized powder at room temperature. |
Usage Statement | Our products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |