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Soluble RANK Ligand (158-316 a.a) Mouse Recombinant


Item#:
rAP-2458
Size Price Quantity
2.0 ug $70.00
10.0 ug $182.00
1000.0 ug $6,552.00
Product Name Soluble RANK Ligand (158-316 a.a) Mouse Recombinant
Synonyms Soluble Receptor Activator of NFkB Ligand, TNFSF11, TRANCE, TNF-related activation-induced cytokine, OPGL, ODF, Osteoclast differentiation factor, Tumor necrosis factor ligand superfamily member 11, Receptor activator of nuclear factor kappa B ligand, RANKL, Osteoprotegerin ligand, CD254 antigen, sRANKL, sOdf.
Description sRANKL Mouse Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain (158-316 a.a) having a molecular mass of 19kDa.The sRANKL is purified by proprietary chromatographic techniques.
Uniprot Accesion Number Q3TWY5
Amino Acid SequenceLys158-Asp316, with an N-terminal Met, Accession # Q3TWY5.
Source Escherichia Coli.
Physical Appearance and Stability Lyophilized sRANKL although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution sRANKL should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Formulation and Purity sRANKL protein was lyophilized from a 0.2µm filtered solution in NaH2PO4, NaCl and EDTA. Greater than 95.0% as determined by SDS-PAGE.
Application
Solubility It is recommended to reconstitute the lyophilized sRANKL in sterile 18MO-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Biological Activity The ED50, as measured by its ability to induce osteoclast differentiation of RAW 264.7 mouse monocyte/macrophage cells, is less than 2ng/ml.
Shipping Format and Condition Lyophilized powder at room temperature.
Usage Statement Our products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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