| Product Name | RANK Ligand Soluble Mouse Recombinant |
| Synonyms | Soluble Receptor Activator of NFkB Ligand, TNFSF11, TRANCE, TNF-related activation-induced cytokine, OPGL, ODF, Osteoclast differentiation factor, Tumor necrosis factor ligand superfamily member 11, Receptor activator of nuclear factor kappa B ligand, RANKL, Osteoprotegerin ligand, CD254 antigen, sRANKL, sOdf. |
| Description | sRANKL Mouse Recombinant produced in E.coli is single, non-glycosylated, polypeptide chain containing 160 amino acids and having a total molecular mass of 17.9kDa. CD254 is purified by proprietary chromatographic techniques. |
| Uniprot Accesion Number | O35235 |
| Amino Acid Sequence | MKPEAQPFAH LTINAASIPS GSHKVTLSSW YHDRGWAKIS NMTLSNGKLR VNQDGFYYLY ANICFRHHET SGSVPTDYLQ LMVYVVKTSI KIPSSHNLMK GGSTKNWSGN SEFHFYSINV GGFFKLRAGE EISIQVSNPS LLDPDQDATY FGAFKVQDID. |
| Source | Escherichia Coli. |
| Physical Appearance and Stability | Lyophilized TNFSF11 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution sRANKL should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. |
| Formulation and Purity | The sRANKL Mouse was lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.0, 200mM NaCl and 0.1mM EDTA. Greater than 95.0% as determined by |
| Application | |
| Solubility | It is recommended to reconstitute the lyophilized sRANKL in sterile 18MO-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
| Biological Activity | The ED50 as determined by its ability to induce osteoclast differentiation of murine RAW 264.7 cells is less than 2 ng/ml, corresponding to a specific activity of > 5.0 × 105 IU/mg. |
| Shipping Format and Condition | Lyophilized powder at room temperature. |
| Usage Statement | Our products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
