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Bone Morphogenetic protein-6 Human Recombinant, Hek


Item#:
rAP-0370
Size Price Quantity
1.0 ug $112.00
5.0 ug $420.00
10.0 ug $672.00
Product Name Bone Morphogenetic protein-6 Human Recombinant, Hek
Synonyms Bone morphogenetic protein 6, BMP-6, VG-1-related protein, VG-1-R, VGR-1, BMP6, VGR, VGR1.
Description BMP-6 Human Recombinant produced in HEK cells is a glycosylated disulfide linked homodimer of two 139 amino acid polypeptide chains; each monomer is expressed as the C-terminal part of a precursor polypeptide, which contains a 20 amino acid signal peptide and a 354 amino acid propeptide.The BMP-6 which has a total molecular weight of 26.2kDa is purified by proprietary chromatographic techniques.
Uniprot Accesion Number P22004
Amino Acid SequenceVSSASDYNSS ELKTACRKHE LYVSFQDLGW QDWIIAPKGY AANYCDGECS FPLNAHMNATNHAIVQTLVH LMNPEYVPKP CCAPTKLNAI SVLYFDDNSN VILKKYRNMV VRACGCH.
Source HEK.
Physical Appearance and Stability Lyophilized BMP-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution BMP-6 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. 
Formulation and Purity The BMP-6 was lyophilized from 10mM Tris, pH 9.0 . Greater than 95.0% as determined by analysis by SDS-PAGE and HPLC analysis.
Application
Solubility It is recommended to reconstitute the lyophilized BMP-6 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Biological Activity The ED50 as determined by its ability to induce alkaline phosphatase production in the ATDC-5 cell line is typically 0.03-0.06 μg/ml.
Shipping Format and Condition Lyophilized powder at room temperature.
Usage Statement Our products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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