Mouse Monoclonal anti-Human CD11a/CD18 (LFA-1) Antibody

Item#:

xAP-0068

Size	Price	Quantity
100.0 ug	$420.00

Catalog Number	xAP-0068
ID	Mouse Monoclonal anti-Human CD11a/CD18 (LFA-1) Antibody
Antigen Description	CD11/CD18 belongs to the integrin family of proteins. It is heterodimeric cell surface receptor expressed on all leukocytes. CD18, in association with integrin a chain CD11a, CD11b, and CD11c forms LFA-1, Mac-1, and aXß2, respectively, and plays an important role in leukocyte adhesion. CD11/CD18 complexes bind ICAM-1 (CD54), ICAM-2 (CD102), ICAM-3 (CD50), iC3b, and fibrinogen. Clone m24 binds the extended/open high affinity conformation of CD11a/CD18. The antibody can be used as a reporter of the activation state of the integrin receptor in response to exposure to Mg2+ or Mn2+.
Size	100ug
Immunogen	Fibronectin-purified human monocytes
Clone	#m24
Antibody Isotype	Mouse IgG1
Host Species	Mouse
Preparation	The antibody was purified by affinity chromatography.
Formulation	The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application	FC
Storage & Handling	Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.