Mouse Monoclonal Antibody to KRT15

Item#:

sAP-0335

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0335
Product Name	Mouse Monoclonal Antibody to KRT15
Target Molecle	KRT15
Aliases	K15; CK15; K1CO; KRT1
Species	Human
MW	49kDa
Enterez GeneID	3866
General Information	The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Keratin 15 is a type I keratin without a defined type II partner. Keratin 15 is expressed primarily in the basal keratinocytes of stratified tissues, including the fetal epidermis and fetal nail. Expression of keratin 15 is downregulated in some hyperproliferating situations, such as psoriasis and hypertrophic scars. Because keratinocytes in psoriasis and hypertrophic scars are activated, it is suggested that keratin 15 expression is not compatible with keratinocyte activation and the keratin 15 gene is downregulated to maintain the activated phenotype.
Immunogen	Purified recombinant fragment of KRT15 expressed in E. Coli.
Clone	MM6E7;
Isotype	Mouse IgG2a
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Proc. Natl. Acad. Sci. 2006.103