Mouse Monoclonal Antibody to CD18

Item#:

sAP-0286

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0286
Product Name	Mouse Monoclonal Antibody to CD18
Target Molecle	CD18
Aliases	LAD; MF17; LCAMB; LFA-1; ITGB2
Species	Human, Mouse
MW	85kDa
Enterez GeneID	3689
General Information	CD18, also known as ITGB2 (integrin beta chain beta 2). Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. CD18 is expressed by most leucocytes. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene.
Immunogen	Purified recombinant fragment of CD18 expressed in E. Coli.
Clone	MM10E12;
Isotype	Mouse IgG2b
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Cell. 1996 Jan 26;84(2)