Mouse Monoclonal Antibody to PEG10

Item#:

sAP-0245

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0245
Product Name	Mouse Monoclonal Antibody to PEG10
Target Molecle	PEG10
Aliases	Edr; HB-1; Mar2; MEF3L; Mart2; RGAG3
Species	Human
MW	Isoform RF1 (37kDa); RF1/RF2 (80kDa)
Enterez GeneID	23089
General Information	PEG10, paternally expressed 10. The PEG10 includes two overlapping reading frames of the same transcript encoding distinct isoforms. The shorter isoform has a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons, and it functions in part by interacting with members of the TGF-beta receptor family. The longer isoform has the active-site DSG consensus sequence of the protease domain of pol proteins. The longer isoform is the result of -1 translational frameshifting that is also seen in some retroviruses. Expression of these two isoforms only comes from the paternal allele due to imprinting. Increased gene expression (as observed by an increase in mRNA levels) is associated with hepatocellular carcinomas.
Immunogen	Purified recombinant fragment of human PEG10 expressed in E. Coli.
Clone	MM4C10A7;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide. ;
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Oncogene. 2007 Aug 23;26(39)