Home Page > ANTIBODY > MONOCLONAL ANTIBODY > Mouse Monoclonal Antibody >  Mouse Monoclonal Antibody to SORL1

Mouse Monoclonal Antibody to SORL1


Item#:
sAP-0123
Size Price Quantity
50.0 ug $320.00
Catalog Number sAP-0123
Product Name Mouse Monoclonal Antibody to SORL1
Target Molecle SORL1
Aliases SORL1
Species Human
MW N/A
Enterez GeneID 6653
General Information SORL1 (sortilin-related receptor, L A repeats containing) also known as sorting protein-related receptor containing LDLR class A (SorLA), is a Type I membrane protein that may be involved in cell-cell interaction. SorLA, a single transmembrane receptor, binds LDL and transports it into cells by endocytosis. SorLA is synthesized as a proreceptor which is processed to the mature form by a furin-like propeptidase. It can also bind to RAP (receptor-associated protein). SorLA is a multifunctional endocytis receptor important in lipoprotein and protease uptake. The N-terminal propeptide, which is removed, can be cleaved by furin or homologous proteases. Endogenous SorLA binds the neuropeptide head activator (HA) and is important for HA signaling and function. The gene encoding for the protein maps to chromosome 8p23.1. SorLA is expressed mainly in brain (cerebral cortex, cerebellum and the occipital pole), but can also be found in liver, spinal cord, kidney, testis and pancreas.
Immunogen Purified recombinant fragment of human SORL1 expressed in E. Coli.
Clone MM3B6B11;
Isotype Mouse IgG1
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1. Zhu Z. Jiang W. Thompson HJ. Carcinogenesis. 2003, Jul, 24(7)
N
N

ANGIO-PROTEOMIE, ALL RIGHTS RESERVED