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Mouse Monoclonal Antibody to TYRO3
Item#:
sAP-0108
Size Price Quantity
50.0 ug $320.00
Catalog Number sAP-0108
Product Name Mouse Monoclonal Antibody to TYRO3
Target Molecle TYRO3
Aliases BYK; Brt; Dtk; RSE; Sky; Tif; FLJ16467
Species Human
MW N/A
Enterez GeneID 7301
General Information Tyrosine-protein kinase (TYRO3) belongs to the Tyr protein kinase family (AXL/UFO subfamily). The UFO family of receptor tyrosine kinases is comprised of subfamily members Rse(also referred to as Tyro3 or Sky) and UFO (also called Tyro7 or Axl). Two distinct isoforms of Rse, designated Brt and Etk-2, have been described. Brt differs from Rse at its C-terminus, but more importantly lacks the N-terminal 31 amino acid signal peptide sequence present in Rse, which is replaced by a 27 amino acid Brt-specific sequence. It has been suggested that as a result of this alternative splicing event, Brt resides in the cytoplasm, unlike Rse which is expressed on the cell surface. Ekt-2 also lacks an N-terminal signal peptide which is substituted with a 45 amino acid Ekt-2-specific sequence. Protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation.
Immunogen Purified recombinant fragment of TYRO3 expressed in E. Coli.
Clone MM1C10E8;
Isotype Mouse IgG1
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1. Mendez P, Garcia-Segura LM. Endocrinology. 2006 Jun;147(6)
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