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Mouse Monoclonal Antibody to KSHV ORF62


Item#:
sAP-0017
Size Price Quantity
50.0 ug $320.00
Catalog Number sAP-0017
Product Name Mouse Monoclonal Antibody to KSHV ORF62
Target Molecle KSHV ORF62
Aliases ORF62
Species KSHV
MW N/A
Enterez GeneID 4961461
General Information Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and has been closely linked to the Kaposi¿s sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman¿s disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. At least five major proteins are likely to be involved in the assembly of the HHV-8 capsid, including a protease (encoded by ORF17), the major capsid protein (encoded by ORF25), and three other smaller capsid proteins (encoded by ORF62, ORF26, and ORF65). Previous structural studies have shown that the HSV-1 triplex is a monomer of VP19c and a dimer of VP23 and that the HCMV triplex is similarly composed of a monomer and a dimer. By analogy, the KSHV triplexes are likely also composed of a monomer of the ORF62 protein and a dimer of the ORF26 protein, which are the respective homologs of VP19c and VP23.
Immunogen Purified recombinant fragment of human KSHV ORF62 expressed in E. Coli.
Clone MM5B7B6;
Isotype Mouse IgM
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1. Chang Y. et al. 1994. Science. 266

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